Dosing System for Pharmaceutical & Bioengineering Industry

Welcome to the detail page of our Dosing System for Pharmaceutical & Bioengineering Industry. This practical and reliable dosing solution is specially designed for the core processes of pharmaceutical and bioengineering production, including fermenters, cell culture and purification systems. It provides stable and accurate dosing of pH regulators, nutrients, precursors and defoamers. The system is designed with practicality and reliability as the core, which is easy to operate and maintain, and fully meets the general dosing requirements of the pharmaceutical and bioengineering industry.

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Core Functions

Our dosing system is developed around the key processes of pharmaceutical and bioengineering industry, with clear functional positioning and strong pertinence, mainly including the following core functions:

pH Regulator Dosing

Aiming at the pH control needs of fermenters and cell culture processes, the system accurately doses pH regulators (such as hydrochloric acid, sodium hydroxide solution) to maintain the pH value of the reaction system within the set range. It is equipped with a high-sensitivity pH sensor that can monitor the pH change of the system in real time. The metering pump adjusts the dosing amount according to the monitoring data to ensure the stability of the reaction environment.

Nutrient and Precursor Dosing

In the microbial fermentation and cell culture stages, the system automatically supplements nutrients (such as glucose, amino acid solution) and precursors required for product synthesis. According to the pre-set process curve or the feedback of the culture density detector, the system can complete continuous or batch dosing, providing sufficient nutrition for microbial growth and product synthesis, and ensuring the stability of production yield.

Defoamer Dosing

Aiming at the foam problem generated in the fermentation process, the system automatically doses defoamers (such as silicone oil, polyether defoamers) to control the foam height within a reasonable range. It can be linked with the foam level sensor installed in the fermenter. When the foam reaches the set height, the dosing system starts automatically; when the foam decreases, it stops dosing, avoiding excessive addition of defoamer affecting product quality.

Purification System Dosing

In the product purification process, the system accurately doses various auxiliary agents required (such as eluents, cleaning agents) to ensure the effect of purification operations. The dosing process is stable and controllable, which helps to improve the purity of the final product.

Product Features

Process-Oriented Design

Tailored for fermenters, cell culture and purification systems in pharmaceutical and bioengineering industry, the system structure and dosing mode are optimized according to the characteristics of different processes, without redundant functions, which is more in line with the actual production needs.

Stable and Accurate Dosing

Equipped with industrial-grade metering pumps with a dosing accuracy of ±1%~±2%, which can ensure the precise delivery of various agents. The stable dosing performance effectively avoids the impact of dosing errors on product quality and production yield.

Simple Operation and Control

Adopts a concise touchscreen operation interface, which clearly displays the dosing status, agent level and key process parameters (such as pH value, foam height). Operators can set the dosing parameters and start/stop the system with simple clicks, and can master the operation skills through basic training. It also supports manual dosing mode for emergency use.

Reliable and Durable Performance

Key components such as metering pumps, agent storage tanks and pipelines are made of corrosion-resistant materials (304 stainless steel, PTFE) that meet the requirements of pharmaceutical industry, which are compatible with common agents in the industry. The overall structure is solid and durable, suitable for long-term continuous operation in the production environment.

Easy Maintenance

The system adopts a modular design. Metering pumps, filters, sensors and other components can be disassembled and replaced independently. The storage tanks are equipped with transparent observation windows and easy-to-clean structures, which are convenient for daily inspection of agent levels and regular cleaning. Common faults can be eliminated quickly, reducing production downtime.

Flexible Matching

It can be matched with different scales of production equipment, from small laboratory fermenters to large-scale industrial production lines. The number of dosing channels (2-6 channels) can be selected according to the number of agent types used in the production process, and it can be easily connected with the existing production control system.

Main Components

Component Category	Specific Components
Agent Storage Unit	Stainless steel/PTFE storage tanks (with level gauges), tank top breathing valves, sampling ports
Precision Dosing Unit	Frequency conversion metering pumps (mechanical diaphragm type), flow meters, check valves
Detection and Control Unit	pH sensors, foam level sensors, temperature sensors, touchscreen control cabinet
Pipeline and Valve Unit	Stainless steel pipelines, PTFE-lined valves, filters, pressure gauges

Application Scenarios

The system is widely used in the following key processes of pharmaceutical and bioengineering industry, providing reliable dosing support for production operations:

Fermenters

Applied in the microbial fermentation process of antibiotics, vitamins, enzymes and other pharmaceutical products. It doses pH regulators to maintain the optimal pH environment for fermentation, supplements nutrients to promote microbial proliferation, and adds defoamers to control foam. It is suitable for both aerobic fermentation and anaerobic fermentation processes.

Cell Culture

Used in the cell culture process of monoclonal antibodies, vaccines and other biological products. It accurately doses pH regulators to ensure the stability of the cell culture environment, automatically supplements glucose, amino acids and other nutrients according to the cell growth status, and controls foam through defoamer dosing, creating good conditions for cell growth and product expression.

Purification Systems

Applied in the product purification links such as chromatography, filtration and separation. It accurately doses eluents to ensure the elution effect of target products, and adds cleaning agents to clean the purification equipment and pipelines, ensuring the cleanliness of the purification system and avoiding cross-contamination between batches.

If you are looking for a practical and reliable dosing solution for your pharmaceutical or bioengineering production line, or want to know more about the matching plan of the system with your fermenters, cell culture or purification equipment, please feel free to contact us. Our team will provide you with professional consultation and quotation services based on your specific production needs!

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